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A study on human postmortem brain tissue has revealed that the pathological progression of AD is accompanied by decreased expression of nuclear receptor coactivator 4 and GPX4 in gray matter (86)

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5.3.3 Bile acids High-fat diet (HFD) reshapes microbiota-dependent bile acid metabolism and promotes the accumulation of secondary bile acids such as deoxycholic acid (DCA) (152)

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