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Similarly, punicalagin promotes nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, which boosts antioxidant defenses while decreasing apoptosis and inflammation (Al-Khawalde et al

61 In addition, it was one of the most reported lean-associated genera in patients with obesity and metabolic disorders 62 and was found to decrease in patients with diabetes

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2.4.3 Analysis of liver antioxidant indexes Seven bullfrogs were taken from each of the NC, FI and GSH groups for liver tissue extraction, and the livers were quickly put into liquid nitrogen after removal, and then stored in a -80C refrigerator for the detection of liver antioxidant indexes