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The content of CoQ10 significantly increased in GCH1-overexpressing cells, possibly due to the abundant production of its biosynthetic precursor 4-OH-benzoate, which is dependent on BH4-mediated conversion of phenylalanine to tyrosine

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(2015c) showed that exogenous GSH could result in coordinated induction of the antioxidant and glyoxalase systems which effectively reduced oxidative damage and MG toxicity, and improved the physiological adaptation of V

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