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Nevertheless, pharmaceutical companies have pursued the twincretin concept, developing GLP-1/GIP dual agonists such as tirzepatide, an analogue biased in favour of GIP over GLP-1 activity [55], and NNC0090-2746, another analogue with balanced GLP-1 and GIP activity [56]

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This article examines current evidence, explores potential mechanisms, and provides practical guidance for managing sleep-related concerns during Wegovy treatment

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