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GLP-1 medications are synthetic versions of this hormone designed to mimic its effects

At week 5, the dosage is typically raised to 5 mg once a week for another 4 weeks

These findings coincided with a marked maternal body weight loss in both animal species (see Data)

Some healthcare providers may prescribe both off-label in select cases, but this requires careful patient selection, comprehensive cardiovascular screening, and close monitoring for additive side effects including increased heart rate, blood pressure changes, and gastrointestinal symptoms

A study found that while some participants regained weight after stopping semaglutide, many retained a portion of their weight loss by continuing with lifestyle modifications