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The differences in function between type A and type B intercalated cells is due, in part, to the opposing distributions of various transporter proteins which, for example, places a particular transporter in the apical membrane of a type A cell and the same transporter in the basolateral membrane of a type B cell

The nonenzymatic initial reaction between 1 M roGFP2 WT (S 2 ) and physiological millimolar GSH concentrations was too slow to be detectable and to be of any relevance in the presence of glutaredoxins in accordance with previous analyses 32

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These findings have important clinical ramifications with the possibility of targeting ferroptosis pathway in GPX4-overexpressing thyroid cancers