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Research has shown that IGF1 LR3 can synergize with other growth factors such as fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF) to enhance cellular responses

Claudianos C, Ranson H, Johnson RM, Biswas S, Schuler MA, Berenbaum MR

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Furthermore, the decrease in cardiac injury biomarkers (CK, CK-MB and LDH) and the increase in HO-1 expression suggest reduced oxidative stress and enhanced myocardial integrity