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It was originally reported after isolation from rabbit blood, but its precise endogenous precursor and physiological role remain unresolved

For those with chronic conditions like IBD or EPI, ongoing management of the underlying disease is necessary, and periodic B12 monitoring may be recommended to ensure levels remain adequate

Consequently, restoring redox equilibrium represents a promising avenue for overcoming therapy resistance and advancing targeted anticancer strategies that exploit the inherent redox vulnerabilities of malignant cells [33]

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Dosing Framework by Clinical Context and Biomarker Status Glutathione dosing should account for baseline oxidative stress, antioxidant capacity, and individual metabolic factors