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In fact, an optimum ratio of these receptors is required to maintain pregnancy [62]

Preclinical studies show that GLP-1 signaling can reduce inflammatory cytokine production and modulate immune cell activity

These models have provided crucial insights into the immunological pathways that drive autoimmune thyroid diseases and have been essential for developing potential immunomodulatory therapies aimed at modulating the autoimmune response in Hashimotos thyroiditis (Qian et al

Subsequent research in PD mouse models demonstrated a toxic synergy between mutant -syn (-syn-A53T) and iron deposition, inducing cellular senescence in the SN prior to DA neuron loss and the onset of motor deficits (Shen Q