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(5) Additionally, Pinealon has been associated with increased levels of irisin, a peptide that has been implicated in neural differentiation, proliferation, and energy expenditure within the brain
Comment: A commenter recommended CMS collect and disseminate HRSN information since they are better positioned and the HRSN screening falls outside of heart failure and low back pain specialists' clinical scope
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At 425.600, we proposed to redesignate paragraph (h) as paragraph (i), and proposed to add a new paragraph (h) that specifies the requirements CMS would use to determine an ACO's eligibility for Shared Savings Program participation options for agreement periods beginning on or after January 1, 2027, as described in further detail in the discussion that follows
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