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In fact, SGLT2-i induced osmotic diuresis and reduction in plasma volume potentially activate systemic RAAS, leading to an initial increase of renin levels in the first three-six months of treatment (53)

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A deeper understanding of astrocyte reactivity will be pivotal for the development of astrocyte-targeted therapeutic strategies aimed at restoring CNS homeostasis and mitigating disease progression

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Talk to your doctor and pharmacist about low blood sugar and how to manage it