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2011;301:R581R600

The drug significantly reduces appetite, which is the point

When to Avoid Alcohol Entirely on GLP-1 Medications Certain patients should not drink alcohol while taking semaglutide, tirzepatide, or other GLP-1 drugs

Moreover, the acute lipid-lowering actions of GLP-1RA are independent of the control of islet hormone secretion or gastric emptying and inhibited by the GLP-1R antagonist exendin (939), consistent with a key role for the canonical GLP-1R in the control of postprandial TG secretion (9, 10)