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That final 5 mg escalation delivers only about 1 additional percentage point of weight loss while significantly increasing side effect exposure

In humans, direct ANP infusion at maximal dose increases lipolysis greater than 10-fold (114) and can decreases blood pressure, and increases post-prandial lipid oxidation and energy expenditure (111), suggesting therapeutic benefits of ANP treatment are possible in man

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Ng et al., Journal of Endocrinology found that AOD-9604 stimulates lipolysis and inhibits lipogenesis in adipose tissue without impacting growth-promoting pathways

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