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With increased popularity of GLP-1 drugs to treat obesity and diabetes, concern has risen that use may come with serious side effects

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Clinical Translation: Subsequent studies have confirmed these laboratory findings in human subjects, showing that topical and systemic GHK-Cu increases measurable collagen deposition and improves skin structural integrity over 8-12 weeks of use

In one study, among patients with non-small cell lung cancer treated with anti-PD-1/PD-L1, those who received corticosteroids to manage their irAE had reduced clinical benefit from immunotherapy, with shorter progression-free survival and overall survival

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