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These medications really only act to reduce the effects of circulating thyroid hormones by reducing T4 to T3 conversion (6) and blocking the receptor effects of thyroid hormone

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Right upper quadrant pain, fever, or yellowing of the skin/eyes (possible gallbladder disease) Extreme fatigue or weakness that interferes with daily activities Hair loss, brittle nails, or other signs of nutritional deficiency Symptoms of hypoglycaemia (particularly in patients taking insulin or sulfonylureas concurrently) New or worsening depression or anxiety related to eating difficulties Severe or ongoing constipation with abdominal distension Patients experiencing any of these symptoms should contact their GP promptly