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doi: 10.3389/ftox.2025.1670769 Received 22 July 2025 Accepted 16 September 2025 Published 29 September 2025 Volume 7 - 2025 Edited by Parames C
In research environments, glutathione is recognized for its involvement in oxidative stress regulation, cellular detoxification pathways, and immune system signaling
A high amount of GSSG indicates a cell has suffered oxidative stress, a process believed to contribute to cell aging, breakdown, malfunction (such as cancer) and eventual death
not FDA-approved and used only in a research context
High glucose conditions trigger physiological and pathological conditions in tissues, together with enhanced accumulation of advanced glycation end products (AGEs), which successively cause epithelial tissue necrobiosis and lesions in retinal capillaries (65)
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