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Association of Official Analytical Chemists, Washington, DC Barros MM, Lim C, Klesius PH (2002) Effect of soybean meal replacement by cottonseed meal and iron supplementation on growth, immune response and resistance of channel catfish ( Ictalurus punctatus ) to Edwardsiella ictaluri challenge

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In that case, their end-of-life quality can be significantly decreased and have further negative implications on their disease progression, possibly leading to an earlier death as well

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In some cases, patients may be entirely non-responsive or experience adverse side effects