It mimics the GLP-1 hormone to increase insulin release, reduce glucagon secretion, and slow stomach emptying
A composite of cerebrovascular events was defined as the first occurrence of stroke (haemorrhagic or ischaemic stroke), transient ischaemic attack, cerebral infarction, carotid intervention or surgery [19, 20]
The evidence sits with the molecules: STEP (semaglutide for weight management, NEJM 2021), SURMOUNT (tirzepatide for weight management, NEJM 2022), and SURMOUNT-OSA (tirzepatide for obstructive sleep apnea, NEJM 2024)
Aim for at least 150 minutes of moderate-intensity aerobic exercise or 75 minutes of vigorous-intensity aerobic exercise per week
Many patients taking Ozempic have underlying conditions such as obesity or cardiovascular disease that independently cause breathlessness