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Redox Active -Lipoic Acid Improves Mitochondrial Dysfunction (Int J Mol Sci, 2022) Study shows that alpha-lipoic acid improves mitochondrial function and increases ATP production

It interacts with multiple systems in the body including the nitric oxide (NO) pathway, growth hormone receptors, and angiogenic regulators like VEGF (vascular endothelial growth factor) to promote tissue repair, reduce oxidative stress, and modulate the immune response

149151 The mechanism of antibacterial and antimicrobial activity is generally due to the electrostatic interactions with microbial cell membranes of anionic phospholipids

It is also possible that in active acromegaly, chronic exposure to elevated IGF-I levels resets IGF-IR responsiveness via the induction of IGF-IR resistance (70), as it has been demonstrated that prolonged stimulation with IGF-I induces functional IGF-IR resistance in vitro through the negative feedback loop (72)

PMID: 17147644 Alven, S., Peter, S., Mbese, Z., & Aderibigbe, B