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developed a nanoencapsulated formulation that achieved targeted delivery while improving chemical stability (154)

Acute toxicity Acute toxicity tests on L-SLNs were executed following OECD 423 guidelines

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One observation the table does support: the 3-unit measurement required for 100 mcg from a 10 mg vial sits near the practical accuracy floor of a U-100 syringe, where a one-unit error is a 33% dosing error

[1] Although water-soluble vitamins are generally excreted through urine when consumed in excess, vitamin B12 is unique in that significant amounts are stored in the liver