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However, research does not currently support the claim that vitamin B12 reduces this risk

However, no published randomized controlled trial has compared the combination head-to-head against either ingredient alone in healthy adults, so the additive benefit is not established by clinical data

In addition, when treating low-risk gestational trophoblastic neoplasia with methotrexate, oral vitamin A supplements (6,000 IU/day) were found to decrease tumor markers and chemoresistance in these patients (18)

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These results suggested that chronic hypoxia resulted in an increase in p--syn phosphorylation and abnormal aggregation