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its knockout impairs LPA-induced pancreatic cancer cell migration ( 2.3 Non-canonical LPA receptors In recent years, several additional transmembrane proteins have been identified as non-canonical LPA receptors, including the GPCRs GPR87, GPR35, and P2Y10, as well as the ion channel TRPV1 ( 50 36 nM), coupling to Gq to mobilize intracellular Ca 2+

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