Peripherally acting anti-obesity medicines with evidence for use in older adults Orlistat Weight loss trials None of the XENDOS trial participants were older adults, and hence the results from this study may not be applicable to an ageing population, although as the drug works peripherally there is no reason to suggest reduced efficacy or safety in elderly patients
"Now that GLP-1based therapies have been shown to increase the risk of pancreatic inflammation and abnormal cell proliferation, further studies are needed to urgently clarify whether these linkages lead to pancreatic cancer with long-term use." Study co-authors, in addition to Butler and Atkinson, are Alexandra E
More research efforts are needed to guide dose adjustments and identify the optimal duration of holding GLP-1 RAs prior to scheduling EGD procedures
Safety Profile and Side Effects Phentermine may cause: Increased heart rate Elevated blood pressure Insomnia Dry mouth Restlessness Headaches Dizziness These effects tend to surface early in treatment
For many patients, this initial phase of adjustment is temporary and manageable with a few simple strategies: Eat Small, Frequent Meals : Large meals can overwhelm your GI system