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Spironolactone has been shown to directly reduce sebum production when dosed 50 to 200mg daily

Of the 45 participants included in the research, 29 underwent the endoscopic procedure, while 16 received a sham treatment

Curr Opin Investig Drugs 8(4):312317 Fallah F, Mahdavi R (2023) L-carnitine and synbiotic co-supplementation: beneficial effects on metabolic-endotoxemia, meta-inflammation, and oxidative-stress biomarkers in obese patients: a double blind, randomized, controlled clinical trial