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In diet-induced obese (DIO) mouse models, NNMT inhibition led to approximately 35% reduction in white adipose tissue mass compared to controls

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In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost

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