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For example, people who maintain a vegetarian or vegan diet, people with absorption disorders, and those taking prescription meds like Metformin, Proton Pump Inhibitors (PPIs), and H2 blockers like Pepcid are often at greater risk

Diarrhea, vomiting, constipation, abdominal pain, and decreased appetite also occur in a meaningful minority of patients on both drugs

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Contrave is FDA-approved for chronic weight management in adults with a BMI of 30 or higher (obesity), or a BMI of 27 or higher with at least one weight-related condition such as type 2 diabetes, high blood pressure, or high cholesterol