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We reviewed the legal and regulatory status of each compound in the United States, including FDA approval status and WADA's prohibited list

However, a much repeated criticism of studies of MSG taken without food is that the characteristic strong flavor of MSG is difficult to mask, unblinding the subjects to its identity and potentially leading to bias. Even in people who self-identify as MSG sensitive, studies have failed to provide reproducible evidence of an MSG effect. The authors of the largest and most comprehensive of such studies concluded that large doses of MSG given without food may elicit more symptoms than a placebo in individuals who believe that they react adversely to MSG

Our latest publication, Considerations and interactions with GLP-1 receptor agonists, summarises common issues highlighted to SPS by healthcare professionals with GLP-1 receptor agonists

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