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In this study, we investigated the effects of dysregulated glutathione homeostasis, a principal feature of oxidative stress, on TNF-induced hepatotoxicity and its mechanistic implications in NAFLD progression

S100A15 protein is predictively composed of 101/104 amino acid residues, in which 13-48 residues contain the N-terminal non-canonical EF-hand domain, and 50-85 residues contain the canonical C-terminal EF-hand motif (168) ( Figure 1 )

Both drugs share the same dual-agonist mechanism, differing primarily in their peptide chemistry, pharmacokinetic profiles, and clinical development strategies rather than fundamental pharmacology

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Drug-induced haemolysis and methaemoglobinaemia in glucose 6-phosphate dehydrogenase deficiency