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Wait 4-6 weeks at the new dose before assessing symptom response

Step 2: Draw Bacteriostatic Water Using Aseptic Technique Calculate the volume of bacteriostatic water required based on your target concentration

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Statistical analysis We characterized the baseline characteristics of the combination and monotherapy groups by reporting frequency distributions (counts and percentages) for categorical variables and descriptive statistics (means and standard deviations [SDs]) for continuous variables