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Finally, we investigated the molecular mechanism by which VRK2 promotes GSH biosynthesis and found that VRK2 drives the trafficking of SLC7A11 through phosphorylating Sec24C

However, the consistent prevalence of side effects across studies highlights the importance of patient education, tailored dosing regimens, and close monitoring to mitigate these issues

Dig Liver Dis Off J Ital Soc Gastroenterol Ital Assoc Study Liver 55:2128

The positive effects of the diet are attributed to maintaining a state of nutritional ketosis, which is also a marker for compliance to the diet and assessed by elevated levels of ketone bodies such as acetoacetate in the urine, beta-hydroxybutyrate (BHB) in the blood, and acetone in the breath (7, 8)