The risks fall into three buckets Common, mild, self-limiting Bruising or soreness at the catheter site Cool sensation along the arm during the drip Warm flush or metallic taste, especially with magnesium or B-complex Mild lightheadedness if the drip runs too fast Uncommon Phlebitis, or vein irritation, especially with stronger or more concentrated formulas Infiltration (fluid leaking under the skin if the catheter shifts) Allergic reactions to specific ingredients, particularly thiamine and B-complex Rare but serious Infection at the IV site Fluid overload in patients with heart, kidney, or liver disease Electrolyte disturbances, especially with high-dose magnesium, potassium, or calcium Red blood cell problems in people with G6PD deficiency, a genetic enzyme issue
Oxalate, inflammasome, and progression of kidney disease
10.1172/JCI163669 134 PietrangeloT.FulleS.CosciaF.GigliottiP
Set baseline metrics
Based on another RCT, a single dose of B12 (500 g/d) or its combination with B1(300 mg/d), B6 (80 mg/d), and B9 (2mg/d) during 12 weeks had favorable effects on the frequency of headache attacks and migraine disability (73)
