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Abstract Background Advanced maternal age is associated with decreased oocyte quantity and quality and in vitro fertilization (IVF) success rates

Cells can die through regulated cell death or accidental cell death [35]

337 Additionally, fibroblast growth factor 21 mitigates liver fibrosis and injury induced by iron overload by preventing ferroptosis in hepatocytes

The released drug molecules can then exert their therapeutic effects, such as inducing apoptosis in cancer cells

8 The body requires a delicate balance between production and detoxification/transport of harmful reactive species and protein adducts, and when these defenses are overwhelmed at hepatotoxic doses of APAP, the glucoronidation and sulfonation pathways become saturated, pushing the majority of APAP to be metabolized to NAPQI by the CYP 2E1 pathway and resulting in GSH depletion and build-up of toxic NAPQI