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It is a fat-soluble compound that can span the entire cell membrane

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2.3 Transporters in the HUA network The exchange of uric acid is mediated by various molecules expressed in the epithelial cells of the renal proximal tubules and intestinal epithelial cells, primarily including GLUT9, URAT1, and human ABCG2, OAT1, OAT3, and OAT4 (Figure 3)