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Activation of initiators like caspase-9 and caspase 8 in the intrinsic or extrinsic pathways, respectively, promotes the activation of executioner caspases and pro-apoptotic pathways causing DNA injury and apoptosis (Calopa et al

Ethics statement All animal studies were approved by the Ethics Committee of the Second Hospital of Shandong University (Approve number: KYLL-2018(LW)038)

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Jia ML, Wu M, Zhang L, Zhang X, Zhai Q, Jiang T, et al

My personal opinion based on available evidence is this: If you want to look good and remain healthy - my gut tells me to stay as far away from GLP-1 agonists as you can