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[16] Although cyanocobalamin lacks a defined upper-toxicity threshold due to its water solubility and renal elimination, exceptionally high cumulative doses have been temporally associated with acneiform eruptions, altered potassium homeostasis, and theoretical thrombotic risk, emphasizing the importance of evidence-based dosing
Oncol Nurse Advis IM Talevi A, Quiroga PAM (2018) ADME Processes in Pharmaceutical Sciences (Dosage, Design, and Pharmacotherapy Success)
Vitamin B12 deficiency is generally treated with intramuscular injections of vitamin B12, but people can also be treated with high oral doses
The issue is proceeding without a clear clinical framework for sequencing, inflammation control, and tissue readiness
Very rare but more serious side effects include irregular heartbeats/ palpitations or in extremely rare cases can cause an allergic reaction (anaphylaxis) but I have an EpiPen at hand to treat you immediately should this extremely rare occurrence happen.
