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Alcohol reduces prefrontal cortical serotonin and dopamine activity during the post-drinking period, producing rebound dysphoria, irritability, and anhedonia that can last 24 to 72 hours after the acute intoxication resolves

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If youve opened the pack, you can only keep them frozen for up to six months

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[167] It was originally notated in the Peruvian Paso and thought to be a condition of overwork and older age, but it is being recognized in all age groups and all activity levels